Sodium Taurocholate Stimulates Campylobacter jejuni Outer Membrane Vesicle Production via Down-Regulation of the Maintenance of Lipid Asymmetry Pathway

Campylobacter jejuni outer membrane vesicles (OMVs) contain numerous virulence-associated proteins including the cytolethal distending toxin and three serine proteases.As C.jejuni lacks the classical virulence-associated secretion systems of other enteric pathogens that deliver effectors directly into target cells, OMVs may have a particularly impo

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De Novo MET-amplified NSCLC treated with savolitinib achieved remarkable tumor regression: a case report and review of literature

Abstract Primary MET amplification is an infrequent tumorigenic driver gene alteration identified in pulmonary neoplasms.Data on the effectiveness of MET-tyrosine kinase inhibitor (TKI) therapy in de novo MET amplification are relatively scarce, and there remains a dearth of empirical evidence supporting the use of bostik universal primer pro preci

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